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Methadone is indicated for the maintenance treatment of opioid dependency (i.e. opioid use disorder per the fifth edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM). A 2009 Cochrane review found that it was effective in retaining people in treatment and in the reduction or cessation of heroin use as measured by self-report and urine/hair analysis but did not affect criminal activity or risk of death. Want Pain Relief medication? You can Buy it online –Buy methadone 10mg online here. Methadone Binds to opiate receptors in the CNS. Buy Methadone Online without prescription. It alters the perception of and response to painful stimuli while producing generalized CNS depression. Therapeutic Effects: Decrease in the severity of pain. Suppression of withdrawal symptoms during detoxification and maintenance from heroin and other opioids.
The treatment of opioid-dependent persons with it will follow one of two routes. it maintenance therapy (MMT) is prescribed to individuals who wish to abstain from illicit drug use but have failed to maintain abstinence from opioids for significant periods. The duration of its maintenance ranges from a few months to lifelong. It reduction programs are suitable for addicted persons who wish to completely stop using drugs.
The length of the reduction program will depend on the starting dose and speed of reduction, this varies between clinics and from person to person. In addition, enrollment in methadone maintenance has the potential to reduce the transmission of infectious diseases associated with opiate injection, such as hepatitis and HIV. Want Pain Relief medication? The principal goals of its maintenance are to relieve opioid cravings, suppress the abstinence syndrome, and block the euphoric effects associated with opioids.
However, it abuse does carry the potential for dependence. When used correctly, methadone maintenance has been found to be medically safe and non-sedating and provides a slow recovery from opioid addiction. It is also indicated for pregnant women addicted to opioids. Want Pain Relief medication?
1. For the treatment of moderate to severe pain not responsive to non-narcotic analgesics.
2. For detoxification treatment of opioid addiction (heroin or other morphine-like drugs).
3. For maintenance treatment of opioid addiction (heroin or other morphine-like drugs), in conjunction with appropriate social and medical services.
Methadone is contraindicated in patients with a known hypersensitivity to methadone hydrochloride or any other ingredient. Methadone is contraindicated in any situation where opioids are contraindicated such as patients with respiratory depression (in the absence of resuscitative equipment or in unmonitored settings), and in patients with acute bronchial asthma or hypercarbia. Methadone is contraindicated in any patient who has or is suspected of having paralytic ileus. Methadone should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. Pediatric Use Safety and effectiveness in pediatric patients below the age of 18 years have not been established. The major hazards of methadone are respiratory depression and, to a lesser degree, systemic hypotension. Buy Methadone Online without Prescription.
Adverse effects of methadone:
- Diarrhea or constipation
- Perspiration and sweating
- Heat intolerance
- Dizziness or fainting
- Chronic fatigue, sleepiness, and exhaustion
- Sleep problems such as drowsiness, trouble falling
- asleep (Insomnia), and trouble staying asleep
- Constricted pupils
- Dry mouth
- Nausea and vomiting
- Low blood pressure
- Difficulty urinating
- Mood changes, euphoria, disorientation
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